Growing up in the rural town of Pattiveeranpatti, Tamilnadu, India, Dr. Sadayappan was destined to be a coconut farmer. However, with guidance from his parents, he decided to take a very different path as a scientist. Based on his fascination with plant life on the farm, he would go on to receive his undergraduate degree in Botany. Armed with innate academic ability and a thirst for more knowledge, he continued his graduate and doctoral studies, taking a long road leading, finally, to the post of Professor of Internal Medicine at University of Cincinnati. With his expertise in molecular cardiology, Sadayappan established his lab in 2009, and since then, he has been committed to investigating the regulatory, structural and functional role(s) of the striated muscle protein, myosin binding protein-C, in health and disease.
Establish an integrative, multidisciplinary research, training and education program dedicated to solving the intractable problems associated with cardiovascular and skeletal muscle biology.
Sadayappan Lab provides opportunity for graduate students to do lab rotation, who are from integrated biology and physiology programs.
We will examine the association between cardiac myosin binding protein-C degradation and cardiac dysfunction, leading to the development of potential cardioprotective .....
The long-term goal of Sadayappan lab is to delineate the role of myosin binding protein-C regulation and function in the heart. For more information and to access all our publications,
Sakthivel Sadayappan, PhD, MBA, FAHA
Professor and Head
Department of Cellular & Molecular Medicine
Associate Director, Sarver Heart Center
Czarina M. & Humberto S. Lopez Chair for Excellence in Cardiovascular Research
University of Arizona College of Medicine
Tucson, AZ 85724-5217, USA
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